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Irritability is a common sign of anxiety because it reflects an individual's heightened sensitivity and emotional response to stressors. When a person is anxious, they may feel overwhelmed or unable to cope with their surroundings, which can lead to frustration or irritability. This response can manifest as a short temper or difficulty in managing emotions, often resulting in conflicts or challenges in social interactions.

The other options don't effectively align with typical manifestations of anxiety. Calmness and satisfaction indicate a sense of peace and well-being, which contrasts sharply with the feelings associated with anxiety. Feeling tired, while it can occur due to anxiety-related fatigue, is not as direct a sign as irritability. Therefore, irritability serves as a more pronounced indicator of the emotional turmoil that often accompanies anxiety.